It is very common to have palpitations with CFS. Chest pain and shortness of breath are also common, sometimes followed by an irritating cough that doesn’t go away. Difficulty breathing can also be a symptom of CFS, but is less common. In? other words, it is all very likely to do with your CFS. Hope I helped. Do you have anxiety or depression? CFS can cause them and they also can cause palpitations.