Case Western Reserve Awarded $1.9M Grant for Psoriasis …

Newswise A dermatology researcher at Case Western Reserve University School of Medicine has secured a five-year, $1.9 million federal grant to explore whether a specific molecule may play a pivotal role in the development and progression of psoriasis.

Nicole Ward, PhD, assistant professor of dermatology, is investigating whether interleukin-17C (IL-17C), a protein key to the regulation of the immune system, may also play a role in the onset and escalation of psoriasis, a chronic, debilitating skin disease that affects an estimated 7.5 million Americans.

The award, from the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), part of the National Institutes of Health, is the second Research Project Grant (R01) Ward has received in the last eight months. This grant will allow her to build upon earlier research suggesting a relationship between IL-17C and another protein (called TNF-alpha) in the emergence of psoriasis.

Psoriasis, an inflammatory autoimmune disease, is characterized by raised areas of red, scaly, itchy and sometimes painful patches of skin. Earlier this year, Ward and colleagues published an article in the Journal of Immunology that reported that psoriasis patients have elevated levels of IL-17C in their skin. Following treatment with TNF-alpha inhibitors, a standard therapy, IL-17C levels drop rapidly, even before the skin visibly improves. This development suggests that the presence, or interaction, of IL17-C and TNF-alpha are critical for the pathogenesis of the disease.

Ward and her colleagues also found that mice genetically engineered to overproduce IL-17C in the skin develop spontaneous lesions that resemble human psoriasis, suggesting a potential critical role for this molecule in disease initiation.. She now hopes to identify how IL-17C synergizes with other inflammatory molecules to cause diseasean understanding that may help identify a new target for drug development.

Although psoriasis is among the most common autoimmune diseases in the country, its cause remains unknown. While treatments to alleviate the condition exist, psoriasis has no cure. Patients are also more likely to be diagnosed with inflammatory bowel disease, cardiovascular disease, and depression. Even more troubling, psoriasis patients generally die seven to 10 years earlier than those without the disease.

Research funded by the NIAMS grant will be directed by Ward with collaborators and co-authors of the Journal of Immunology paper, Thomas McCormick, PhD, of Case Western Reserve, and Johann Gudjonsson, MD, PhD, and Andrew Johnston, PhD, of the University of Michigan.

In addition to the NIAMS grant, Wards research is supported by the National Psoriasis Foundation, the Murdough Family Center for Psoriasis and additional grants from the National Institutes of Health.

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About Case Western Reserve University School of Medicine Founded in 1843, Case Western Reserve University School of Medicine is the largest medical research institution in Ohio and is among the nations top medical schools for research funding from the National Institutes of Health. The School of Medicine is recognized throughout the international medical community for outstanding achievements in teaching. The Schools innovative and pioneering Western Reserve2 curriculum interweaves four themes&research and scholarship, clinical mastery, leadership, and civic professionalism&to prepare students for the practice of evidence-based medicine in the rapidly changing health care environment of the 21st century. Nine Nobel Laureates have been affiliated with the School of Medicine.

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Catholic Sentinel | Advertising Sales Representative | Mac's List

Posted: 4/1/2013 – 4:22 pm

Location: Portland

Closing Date: open until filled

Industry: Nonprofit

Type: Full Time

Description:
The Advertising Sales Representative’s primary function is to sell print and web advertising in the Catholic Sentinel, El Centinela, CatholicSentinel.org, ElCentinelaCatolico.org, and Oregon Catholic Directory. This person will participate in the development and execution of strategies to expand the customer base and key advertiser revenue opportunities. This involves evaluating market information, researching potential new revenue streams, and identifying, proposing and selling solutions that meet or exceed customer business expectations.


Key Duties:


· Meet and exceed revenue goals by generating advertising sales

· Identify and create strategies to increase advertising revenue

· Develop relationships with prospective and existing customers

· Formulate and organize ad promotions and follow through on maintenance of accounts and renewals

· Ensure weekly sales focus and activity is balanced with current and projected issues, ensuring consistent ad lineage in all publications

· Proof ads

· Efficiently maintain and utilize customer databases

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· Participate in regular forecasts and performance reviews

· Support other department personnel in sales and administrative efforts

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Job Experience and Education Requirements:


· High school diploma and three to five years successful advertising sales experience




Specialized Skills:


· Strong understanding of advertising, media, research and marketing

· Proven creative/persuasive sales abilities to increase advertising revenue in tight economy and competitive market

· Strong interpersonal communication skills with strong customer focus and knack for negotiation

· Excellent organizational skills with ability to work well under the pressure of deadlines and to handle multiple priorities

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· Ad layout and copywriting experience helpful

· Basic computer skills, including Microsoft Office projects and database skills

· Able to react to change productively and to efficiently handle other essential tasks as assigned

· Bilingual (English/Spanish) beneficial

· Knowledge of Catholic faith beneficial

Application Guidelines/Contact:
Please apply at http://www.ocp.org/careers or send cover letter and resume to sentinel@catholicsentinel.org. We prefer that applicants apply online. No calls please.

Salary:
DOE

Application Url:
http://www.ocp.org/careers

Please mention Mac’s List when applying for this opportunity.


National Psoriasis Foundation | Executive Assistant | Mac's List

Posted: 3/29/2013 – 3:22 pm

Location: Portland

Closing Date: open until filled

Industry: Nonprofit

Type: Full Time

Description:
A national, nonprofit patient advocacy organization located in Portland, Ore, is seeking a full time, professional, self-motivated and organized individual to serve as our Executive Assistant. This individual will have the opportunity to handle a broad range high-level administrative support activities for the day-to-day operations of the President & CEO. Requirements include a Bachelor’s degree with a minimum of three plus years of experience as an executive assistant, advance knowledge of Microsoft products, meeting planning and travel management experience, excellent written, oral and interpersonal communication skills, good attention to detail and the ability to multi task. Experience working with nonprofit board a plus.

Application Guidelines/Contact:
Please forward your resume with your salary requirements to: Human Resources, National Psoriasis Foundation, 6600 SW 92nd Ave., Suite 300, Portland, OR 97223, Fax (503) 245-0626, E-mail hr@psoriasis.org


Salary:
Depending on Experience

Application Url:
Information not posted

Please mention Mac’s List when applying for this opportunity.


DEPUTY DIRECTOR – Finance and Operations – Mac's List

Posted: 3/28/2013 – 4:19 pm

Location: The Dalles, Oregon

Closing Date: open until filled

Industry: Health Care

Type: Full Time

Description:
Are you looking for a leadership position in a behavioral health organization whose vision is to “empower people to make positive changes and is committed to a community system of care?” If so, Mid-Columbia Center for Living located in the heart of Oregon’s Columbia River Gorge, may just be the place for you!


JOB SUMMARY: We are currently seeking to fill our position of Deputy Director Finance and Operations, in The Dalles, Oregon. This executive leadership position is responsible for oversight of finance, business support, human resources and management information systems for the agency which provides a wide range of services in Mental Health, Alcohol, Drug and Gambling, and Developmental Disabilities to adults, children and families across three counties.


MINIMUM REQUIREMENTS: Bachelor’s degree in accounting or business administration, or health administration with an MBA and CPA preferred


Demonstrated increasing responsibility in management roles.


At least four years of experience in some combination in accounting, budgeting, data analysis, management database/information systems, human resources and payroll.


Any equivalent combination of related education, experience, and/or training will be considered.


Please see full job description and requirements on our website at www.mccfl.org/employment.htm.


MCCFL is an Equal Opportunity, ADA Compliant Employer and Drug-free Workplace

Application Guidelines/Contact:
Please go to our website, view the job listing and full description, and then download and complete our application. You may email your cover letter, resume and the application to the following address: hr@mccfl.org or mail it to: MCCFL, 312 E. Third Street, The Dalles, Oregon 97058, Attention: HR

Salary:
Salary: $6,845 – 8,008/mo.

Application Url:
http://www.mccfl.org

Please mention Mac’s List when applying for this opportunity.


Clackamas County | Community Affairs Supervisor | Mac's List

Posted: 3/27/2013 – 9:51 am

Location: Oregon City

Closing Date: 4/2/2013

Industry: Government

Type: Full Time

Description:
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The Clackamas County department of Public and Government Affairs is currently seeking a Community Affairs Supervisor who will serve as a key member of the Public Affairs team. The incumbent will help develop strategic communication, citizen involvement and public outreach plans for the County and will then lead a team to implement those plans. Duties will encompass all aspects of a robust public affairs division for a high-profile local government.


The Community Affairs Supervisor is responsible for identifying sensitive or controversial issues related to department programs and activities that may be of interest to the general public, County Administration or PGA. Incumbents plan, organize and supervise the formulation of effective communication plans for review with PGA and County Administration. Incumbents will keep departments compliant with countywide public information, media relations, and public outreach policy and develops department processes and procedures for effectively and consistently communicating department’s programs and mission to citizens and groups.


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– The most competitive candidates will possess some or all of the following knowledge and/or experience:


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– Understanding of a public sector organization and function of local government departments and agencies


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Applicants for this position must meet the requirements of the County’s Driving Policy. DES will conduct a driving record check prior to finalizing any employment offer or departments may offer employment contingent on receiving a successful driving record check.


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Please note that he testing and selection process for this recruitment will include the following steps:


Oral Board Panel Interviews & Written Exercise are tentatively scheduled during the week of April 8, 2013. Candidates invited to this step of the process will be asked to bring copies of their cover letter and resume.


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This position is included in the County’s alternate workweek program, working 40 hours during a standard workweek of Monday through Thursday (Fridays off). Specific hours of work will be discussed with the candidate selected for this position at the time an offer of employment is extended.

Application Guidelines/Contact:
APPLICATION PROCESS


Clackamas County only accepts on-line employment applications. Emailed, faxed or hard copy applications will not be accepted.


A fully completed Clackamas County On-line Employment Application must be received electronically by the Department of Employee Services, NO LATER THAN 11:59 PM (Pacific Time) ON THE CLOSE DATE. Note: Attaching a resume does NOT substitute for completing the entire on-line employment application.


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Please do not wait to electronically submit your application on the close date as there is no technical support available after business hours.


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Dead Sea Salts- Healthy or Harmful? | No-Nonsense Beauty Blog

QandA3-smQuestion:  My neighbor  brought me back a small bag of  Dead Sea  Salts  from her trip to Israel.  She says its good for  my skin.  But my cardiologist has told me to cut back on salt to lower my blood pressure.  Who is right?

Answer: While it is certainly true that excess dietary salt   is not good for both your heart and yourskin, Dead Sea Salts  have significant health benefits. How?  One of the reasons  is that rather than just plain sodium chloride, Dead Sea Salts are actually a mixture of beneficial minerals.   The sodium chloride content is actually much much higher in traditional ocean water than in the water in the Dead Sea.

Dead Sea Salts have a payload of healthy minerals including magnesium, iodine, zinc, potassium and sulfur.  A study published  in the International Journal of Dermatology, found that  soaking in a a bath enriched  with Dead Sea Salts relieves the pain of  arthritis.  The skin can absorb some of the minerals to  increase circulation.  The National Psoriasis Foundation recommends Dead Sea Salts because the minerals help the skin retain moisture and reduce inflammation. Researchers believe that the psoriasis  skin care benefits can be traced to the magnesium content in Dead Sea Salts.   This essential mineral is known  to bind water to skin cells, normalize skin cell growth and reduce skin roughness.  All good.

You can purchase  bags of pure Dead Sea Salt as well as  in skin care products  which include the salts in their list of ingredients.   Many commerical Dead Sea Salt products are actually made from the mineral-packed mud that is near and in the Dead Sea.   Mud facials with Dead Seal Salts eg  AHVAVA Time to Clear Purifying Mud Mask are especially effective.  These beauty masks soak up excess oil, lift off dead dry skin cells while the magnesium helps the skin plump up with gorgeous moisture.

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Kim Kardashian Praises Tanning Beds While Hawking Her New Self …

‘Tis the season to start working on your tan. And who better to help you than those quintessential and always sun-kissed California girls, the Kardashians?

Despite the lawsuit woes they’re having with their Khroma makeup collection, the Kardashians are expanding their reach into the beauty industry. They’re launching a collection of self-tanners this April called Kardashian Sun Kissed. The five piece range will be carried exclusively at Ulta and retails for $12.99 to $19.99. It’s a three step system, featuring an exfoliation or color maximizing product, the actual tanner itself, and a tan extending product.

READ: Kardashian-Fronted Makeup Line Khroma Served With Injunction

WWD hopped on a call with the enthusiastic Kardashian sisters to chat about the new line.

“I think tanning has really been a way of life for all of us, living in California,” Kim Kardashian told the trade. “Especially, more recently, the need for sunless tan. When I travel, the one thing that makes me feel alive whether or not I have makeup on is a tan, especially in my face. When you travel, you can’t just go lay out.” But while Kim seems to understand why sunless tanners are arguably safer than the real deal or a fake bake, she admits she still uses tanning beds.

“I do like regular tanning because I have psoriasis, and the tanning beds are particularly good for that,” Kim continued. A quick peek on the Mayo Clinic’s website confirms that UV rays, from the sun or from artificial means, are indeed a treatment option for psoriasis. However, The National Psoriasis Foundation does not support the use of tanning beds as a method for treatment, as most tanning beds only use UVA light, not the beneficial UVB light.

PHOTOS: The Kardashians’ sexy bikini bodies

“[We] came up with something that is still good for your skin and healthy for you; everything is paraben- and sulfate-free,” Kourtney said. “We love beauty and fashion, but making sure we’re taking care of our bodies is crucial to us.”

Industry sources are predicting that the Sun Kissed line could sell $10 million at retail.

Tell Us: Will you tan like a Kardashian this summer?

 

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Psoriasis patients flock to social media for practical information …

Marie Ennis-O’Connor is a PR consultant with a passionate interest in healthcare social media and extensive experience of working with healthcare practitioners and patient advocates.

A featured blogger on Webicina and a regular contributor to Health Works Collective an online community for thought leaders in international healthcare, she has been awarded a top blogger accolade by Empowered Doctor.com and most inspiring writer by WegoHealth. Most recently Marie won the best health and wellness blog award in the 2012 Blog Awards Ireland.

Marie is co-founder of #BCCEU, Europe’s first breast cancer social media chat and is a founding member and social media manager for Health2.0 Dublin, part of the Health2.0 international movement.

Marie is an invited speaker at Doctors 2.0™ & You, Cité Internationale Universitaire de Paris, June 6-7, 2013.

LEO Pharma Puts Patients at the Heart of Innovation : Asia Press …

BALLERUP, Denmark, Mar 19, 2013/ PRNewswire-AsiaNet/–

LEO Pharma announces a co-creation agreement with the National Psoriasis
Foundation (NPF) in the United States that puts patients at the heart of LEO
Pharma’s innovation process. The move supports the dermatology company’s aim to
develop future care solutions that address patients’ real-life needs.

The co-creation agreement with the US National Psoriasis Foundation aims to
ensure that the needs of people suffering from psoriasis play a central role in
the development of LEO Pharma’s future psoriasis care solutions. Ultimately,
LEO Pharma hopes that its agreement with NPF will pave the way for improved
care solutions that empower people to better manage their psoriasis.

(Logo: http://photos.prnewswire.com/prnh/20130221/595427 )

“Patients have unique insights into their condition. That is why we are
involving patients as active participants in our innovation process. In order
to make a difference to the everyday lives of people with skin conditions, we
want to gain an understanding of their challenges – and work together to find
solutions,” says Kim Kjoeller, Senior Vice President Global Development, LEO
Pharma.

The co-creation agreement is the latest step in LEO Pharma’s approach to
patient care innovation. This approach – where the pharmaceutical industry
joins forces with external partners, such as patient organisations – is gaining
increasing recognition internationally.

“Healthcare research is at a crossroads. Developing new drugs for the many
conditions that still lack a cure or effective treatment is a costly, complex
and high-risk process, leading some pharmaceutical companies to give up on
entire disease areas. LEO Pharma wants to involve patients in shaping future
care solutions,” adds Kim Kjoeller.

Co-creation with plaque psoriasis patients

LEO Pharma’s co-creation with NPF, which begins on 23 March, is based on
the creation of Psoriasis Frontiers, a group of patients who will meet with LEO
Pharma researchers during a series of workshops. The patients will become an
integrated part of LEO Pharma’s innovation process and focus on investigating
needs, testing new care concepts and exploring new solutions. The first task
will be to consider patient needs in relation to new formulations, devices and
packaging.

The Psoriasis Frontiers group will focus both on conventional
pharmaceutical product innovation and on individualised care solutions such as
patient engagement concepts, access models, diagnostic tools and digital
technologies. Psoriasis Frontiers will act as a sounding board, working only
with concepts and not with marketed products. Specific research findings will
be subject to confidentiality; however, partners are committed to publishing
non-competitive findings to the general public.

“National Psoriasis Foundation recognises the need for patient insight into
research and treatment development. This collaboration will allow people living
with the disease to meet face-to-face with scientists creating the cutting-edge
therapies they may use in their everyday life,” says Kathleen Gallant, chair of
the National Psoriasis Foundation Outreach Committee and member of its Board of
Trustees.

“Who better to discuss product innovation and patient care than people
affected by the disease? Hopefully this ‘patient-focused’ research concept
becomes a trend that creates new opportunities.”

About LEO Pharma

LEO Pharma helps people achieve healthy skin. By offering care solutions to
patients in more than 100 countries globally, the company supports people in
managing their skin conditions.

Founded in 1908 and owned by the LEO Foundation, LEO Pharma has devoted
decades of research and development to delivering products and solutions to
people suffering from skin diseases.

LEO Pharma is headquartered in Denmark and employs around 5,000 people
worldwide.

For more information, visit http://www.leo-pharma.com.

About the National Psoriasis Foundation

The National Psoriasis Foundation is the world’s largest non-profit
organisation serving people with psoriasis and psoriatic arthritis.

Our mission is to find a cure for psoriasis and psoriatic arthritis and to
eliminate their devastating effects through research, advocacy and education.

For more information, call the National Psoriasis Foundation, headquartered
in Portland, Ore., at +1-800-723-9166, or visit http://www.psoriasis.org.
Follow the National Psoriasis Foundation on Facebook
(http://www.facebook.com/national.psoriasis.foundation) and Twitter
(http://www.twitter.com/npf).

SOURCE: LEO Pharma A/S