Blog – Arthritis Treatment Center


Ustekinumab safe and effective for psoriatic arthritis

Phase 3 data from the SUMMIT trial evaluating ustekinumab (Stelara) found it safe and effective in patients with psoriatic arthritis. Ustekinumab blocks the effects of IL12 and IL 23. The drug is FDA approved for psoriasis and investigational for psoriatic arthritis.

Comment: Whether this drug will find widespread use in psoriatic arthritis is going to be interesting to see.

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Psoriasis Essentials – Natural Psoriasis Treatment Guide | Proven …

Psoriasis Essentials - Natural Psoriasis Treatment GuideClick Image To Read More…Important: Others Have Already Discovered That Psoriasis And Related Conditions Such As Psoriatic Arthritis Can Be Treated Naturally… Will you be the next “ex-sufferer” to lead a completely normal life?

“Discover How You Can Stop Suffering From Itchy, Scaly & Embarrassing Psoriasis Naturally… Without Expensive Drugs Or Annoying Side Effects…”

That’s Right – Even if you’ve suffered the embarrassment and pain of psoriasis and psoriatic arthritis for years, you CAN relieve your symptoms and control your condition naturally… without expensive drugs and the nasty side effects that can go along with them…

As a psoriasis sufferer (that IS why you’re here, right?) I don’t need to tell you that psoriasis is much more than an ordinary skin condition. In fact, on top of all the physical symptoms you can suffer because of it, it can also damage your confidence and self esteem… you might even experience anxiety or depression.

Because the outward appearance of psoriasis is, shall we say, not exactly ‘normal’, others may feel uncomfortable when they’re around you. Either they think you have some contagious disease or they simply don’t understand it. They may even avoid you because they don’t know how to act around you.

And to make matters worse, the only way most people know to treat psoriasis is by taking prescription drugs… which can end up costing a fortune AND cause side effects to boot!

Many sufferers also end up developing a related – and more serious – condition called psoriatic arthritis. That’s why it’s so important to get yourself diagnosed and treated as soon as possible when you first notice the signs of psoriasis…

Although it might seem impossible, try to imagine your life without the itching, redness and scaling you’ve come to know so well. What if…

And what if you could enjoy all of these things by treating your psoriasis naturally… without spending a fortune on prescription creams and pills? If all of this sounds like a dream come true, I think you’ll be interested in this…

When I Realized That Countless People Were Treating Their Psoriasis Naturally AND Finding Relief From The Itching And Scaling That Goes Along With It, I Decided To Do Some Research Of My Own…

As you read this, you’re most likely doing some research too… either you have psoriasis or suspect that you do. Or, maybe you know someone who has it and you’re trying to help them by understanding the condition better yourself.

You might even have psoriatic arthritis, a related condition that often develops in psoriasis sufferers. If you already have psoriasis, you should know that you are at risk for developing this arthritis-like condition as well.

One of the things I learned while doing my own research is that there are many different ways of treating and dealing with psoriasis. And while some of them are dependent on drugs and prescribed medications, others are completely natural.

As a natural health enthusiast, I believe that it’s almost always best to treat medical conditions naturally, as long… Read more…

Many psoriasis patients dissatisfied with treatment – Arthritis …

Half of people with psoriasis are not satisfied with the treatment they’re receiving for the skin condition, according to a new study.

Marked by recurring patches of scaly, itchy skin, psoriasis affects about seven million adults in the U.S. and can be treated with topical creams, light therapy and oral medications.

Up to 20 percent of psoriasis patients eventually develop a form of arthritis related to the condition called psoriatic arthritis, according to the U.S. Centers for Disease Control and Prevention.

“Compared to other chronic conditions, patients with psoriasis and psoriatic arthritis may be at particularly increased risk of not receiving adequate treatment,” lead author Dr. April Armstrong, a dermatologist at the University of California, Davis, said.

Although that’s not always a problem for people with mild psoriasis, those with more severe forms of the condition have an increased risk of a range of other health problems, researchers said.

Between 2003 and 2011, more than 5,000 psoriasis or psoriatic arthritis patients in the U.S. filled out surveys about prescription medication use and treatment satisfaction for the National Psoriasis Foundation.

Many psoriaSis patients dissatisfied with treatment Depending on the year, between nine and 30 percent of the almost 1,900 people with severe psoriasis were not receiving treatment, with higher percentages for mild and moderate psoriasis.

Just over half of psoriasis patients and 45 percent of those with psoriatic arthritis reported being dissatisfied with their treatment, according to results published in JAMA Dermatology.

Most people who stopped taking newer injectable and intravenous drugs reportedly did so due to side effects or because the medication wasn’t working.

Some also reported being unable to secure insurance coverage for so-called biologic medications, which include etanercept (marketed as Enbrel) and adalimumab (Humira).

Among patients who discontinued biologic medications in 2008, for example, 25 percent reported it had not worked, 17 percent reported a negative side effect and five percent said their insurance would not pay or they could not afford the medication.

Many psoriaSis patients dissatisfied with treatment The fact that so many patients stopped biologic medications, which are some of the newest and most effective options for severe psoriasis, indicates that better treatments are still needed, Dr. Will Taylor, a rehabilitation medicine specialist who researches psoriatic arthritis at the University of Otago in Wellington, New Zealand, said.

Taylor, who was not involved in the study, noted to Reuters Health that it only included members of the National Psoriasis Foundation, a small percentage of the total number of psoriasis patients in the U.S., which is a limitation.

For people with severe psoriasis, inadequate treatment can be serious because the condition is tied to physical and psychosocial problems, Armstrong said by email.

“Severe psoriasis is associated with increased risk of heart attack, stroke, and cardiovascular deaths,” she said. “Many patients are ashamed of this skin disease and do not wish to go to a barber, a public swimming pool, or be involved in intimate relationships.”

Psoriasis patients are also at increased risk of depression and suicide, Armstrong said.

She has received research grants or honoraria from pharmaceutical companies that make biologic drugs.

Many people may not have access to care or may not understand the severity of potential side effects of psoriasis, which could explain the undertreatment rates, Andrew Robertson, chief medical and scientific officer for the National Psoriasis Foundation in Portland, Oregon, said.

Dermatologists experienced with psoriasis aren’t necessarily available to everyone in every area, and many insurance plans are hesitant to cover biologic medications, which may cost up to $25,000 yearly.

Some plans put psoriasis patients in a “specialty tier,” which could require them to pay as much as 25 percent of the cost of the drug. That practice puts medications out of reach for some patients, Robertson told Reuters Health.

But for mild cases of psoriasis, forgoing treatment may not be a big deal, Taylor said.

The researchers agreed that psoriasis varies widely from patient to patient and treatment should be tailored to individual needs.

SOURCE: JAMA Dermatology, online August 14, 2013

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New Psoriasis Skin Treatment Review – Free Natural Skin Care Tips

New Psoriasis Skin Treatment Review – Natural Skin Care Tips

Visit: for more informationHome remedies for psoriasis are the lowest cost treating dealing with psoriasis. More often than not, they’re all-natural cures and won’t harm you with harsh side-effects. Not every results work for everybody and it may take trying few different remedies to find one that matches your needs. Listed below are some of the most popular home remedies available. The first is a straightforward one, but it’s often overlooked by skin psoriasis sufferers. Moisturize, after which moisturize again. It’s quick, it’s easy and it only takes a few minutes each day. Once the skin is dry and flaky, it may crack and become destroyed. It is essential to keep the skin moisturize on the exterior and the inside. For that outside, use unscented lotions but for the inside drink plenty of water each day. The greater water you drink each day the greater hydrated the skin is going to the skin will become too dry, have a bath or a shower. Or soak the dry, patches of skin to assist them to fall of naturally and without harming the skin. Make use of a mild soap that won’t irritate the skin or cause excessive dryness. Do not take too many long baths as that may remove precious oils in the skin, oils needed to protect the skin externally elements. Lotion soon after bathing to secure the moisture. Every shower or bath should be done in lukewarm water, warm water will cause the skin to itch and just cause further problems. Wet wraps are an excellent home remedy. This remedy is often used immediately after a bath or shower or during the night before bed. After your shower or bath, lotion the body while you normally would to keep within the moisture. Take some ace bandages, or whatever is handy, and soak them in certain lukewarm water. Wrap the bandages round the problem areas like the elbows, knees, or thighs. The wet wraps could keep the areas from recurring or itching and can keep the patchy areas from getting hard or are lots of other things that can be done without having to spend loads of money, an easy internet search or speaking with your doctor will give you a number of other ideas.

Before proceeding additionally, it ‘s worth keeping in mind that not all all-natural skin care products on the market are produced equivalent, and do not essentially fit the interpretation of “secure personal care products. ” Nevertheless, foxglove, nightshade and curare are all “all-natural ” materials– but you would rarely intend to ingest them!

In fact, there is nothing wrong with salicylic acid. An all-natural bodily hormone that is stemmed from white willow and meadowsweet, it has been utilized for centuries to scrub and clean the skin and minimize fever. In fact, it is just one of the active ingredients in aspirin and the anti-biotic tetracycline.

The trouble is that some people could experience allergies from consuming hand and physical body ointment or other personal care products (consisting of ladies’s personal care products) including salicylates. These could be especially awkward when salicylic acid can be found in contact with sensitive mucus membrane layers, and could cause not only rashes, but abdominal pain, problems as well as difficulty in breathing in the most severe cases.

Safe Personal Care Products

Absolutely secure personal care products are devoid of salicylates and alcohol, and could hence be utilized by essentially anybody without concern of adverse effects. These all-natural skin care products include gentler alternatives such as witch hazel and olive oil (utilized in the Mediterranean countries for centuries not only as food but as a cosmetic as well as a lube for equipment!) and also shea butter and other top quality active ingredients. Those that have sensitive and/or delicate skin will experience great advantages by switching over to salicylate-free anti maturing skin care products and alcohol cost-free toner for mild cleansing and exfoliation.

What’s Beneath The Area

Numerous ladies do not really feel completely clothed without effective makeup– but this is only component of the formula. While salicylate and alcohol-free ladies’s personal care products include mineral-based makeup, the reality is that even make-up of the best could only do so considerably. It is very important to have tidy, healthy and balanced skin underneath the makeup, which is where salicylate-free hand and physical body ointment and alcohol cost-free toner is most effective. Good moisturizers with top quality, all-natural active ingredients keep pores from ending up being stopped up by getting rid of the microscopic littles filth that other products miss out on.

This is just several of exactly what all-natural skin care products without alcohol and salicylates could do for you. Unless there is some pathogenic or genetic source (which needs the attention of a dermatologist), there is no reason why consuming salicylate and alcohol cost-free all-natural skin care products ought to not assist you obtain the vibrant, healthy and balanced skin you deserve.

Baby Skin Care Tips

August is National Psoriasis Awareness Month – Pura Vida Bracelets

rsz about1 August is National Psoriasis Awareness Month

Hey PV Fans! August is National Psoriasis Awareness Month so today we wanted to spotlight our Psoriasis/Psoriatic Arthritis Awareness Bracelet! The organization that we donate to is the National Psoriasis Foundation.

Each August, the National Psoriasis Foundation sponsors Psoriasis Awareness Month to raise awareness, encourage research and advocate for better care for people with psoriasis.

psoriasisfoundation1 August is National Psoriasis Awareness Month

National Psoriasis Foundation

“The National Psoriasis Foundation (NPF) is a non-profit, voluntary health agency dedicated to finding a cure for psoriasis and psoriatic arthritis and eliminating their devastating effects through research, advocacy and education.

Founded in 1968, the Psoriasis Foundation has evolved to become the leading patient advocacy group for the 7.5 million Americans living with psoriasis and psoriatic arthritis.

As emerging research continues to demonstrate the serious, systemic effects of these chronic autoimmune diseases, our highest priority is to find a cure.” (National Psoriasis Foundation)

home page header August is National Psoriasis Awareness Month

Psoriatic Arthritis

Up to 30 percent of people with psoriasis also develop psoriatic arthritis, which causes pain, stiffness and swelling in and around the joints.

Psoriatic arthritis can develop at any time, but it most commonly appears between the ages of 30 and 50. Genes, the immune system and environmental factors are all believed to play a role in the onset of the disease.

Early recognition, diagnosis and treatment of psoriatic arthritis are critical to relieve pain and inflammation and help prevent progressive joint damage.

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More Psoriasis facts

Psoriasis is the most common autoimmune disease in the U.S., affecting as many as 7.5 million Americans.

Psoriasis occurs when the immune system sends out faulty signals that speed up the growth cycle of skin cells, resulting in painful red, scaly patches on the body that bleed and itch.

Psoriasis is not contagious.

Psoriasis frequently occurs with a range of other health concerns including diabetes, hypertension, heart attack and depression.

Psoriasis impacts the emotions. Nearly 70% of people with psoriasis say their disease makes them feel self-conscious, embarrassed and helpless.

Up to 30 percent of people with psoriasis also develop psoriatic arthritis, which causes pain, swelling and stiffness around the joints.

There currently is no cure for psoriasis.

481049 10151140817733789 1755810808 n August is National Psoriasis Awareness Month

Life with Psoriasis Photo Contest presented by National Psoriasis Contest

Picture this: If you have psoriasis or love someone who does, enter our Life with Psoriasis Photo Contest held during Psoriasis Awareness Month. This August, submit a photo to National Psoriasis Foundation that depicts your life with psoriasis—with its challenges, breakthroughs, frustrations and achievements.

“We want to see life with psoriasis through your lens. The winner of the Life with Psoriasis Photo Contest will receive a Canon EOS Rebel T3 DSLR camera. Second and third place winners get cool prizes, too.

Deadline for submission is Friday, Aug. 31.” (National Psoriasis Foundation)

pura vida run 120619 0012 1 August is National Psoriasis Awareness Month

To learn more about National Psoriasis Foundation and their contest click HERE. To shop our Psoriasis/Psoriatic Arthritis Awareness Bracelet click HERE.

Probiotic Action Announces New Developments for Psoriasis and …

Recent news from shared information on a new study from the journal of Gut Microbes with information on how the anti-inflammation properties of probiotics are growing in use as a topical probiotic.

Miami, FL (PRWEB) August 15, 2013

Recent reports released from from the Journal of Gut Microbes depicted the growing use of probiotics to help reduce the side effects of skin conditions like psoriasis and rosacea. Whether internally or externally, Probiotics have been known to help reduce inflammation caused by external factors, that disrupt the levels of good and bad bacteria. For skin conditions like acne, psoriasis or rosacea, using the power of probiotics has shown favorable results to reduce swelling, redness, and sometimes infection. As a leader in topical probiotics, Probiotic Action shares industry insight on the science behind using probiotics for skin care.

Eczema, Rosacea, and Psoriasis are skin ailments that are more often related than not. Breaking of the skin associated from immune system and internal imbalances is often inflamed by outlying factors, like bacteria. As bacteria lives naturally on the skin, when a disturbance in body chemistry on the skin’s surface is present, often outbreaks, or redness of the skin increases. The science behind probiotics allows the opportunity for good bacteria to balance the negative reaction of the bad bacteria, resulting in what many patients have seen as reduce breakouts. Probiotics not only help balance the bacteria that reduces breakouts, but also creates an internal balance of bacteria which allows for increased hydration, and fluid delivery to the skin’s inflammation sites.

Fernando Perez, a spokesman for Probiotic Action commented on the success of probiotics for skin care, “We have seen tremendous relief from skin care issues like rosacea and acne, as well as psoriasis. Users who have used our topical probiotic for 10-15 days continuously can experience less redness, breakouts, and smoother skin”.

Perez continued, “The skin is an organ, and just like other systems, it needs a bacteria balance. If physicians recommend probiotics for intestinal organ issues, they should also recommend them for the skin as well”.

For more information on using probiotics for acne, and the science behind probiotic action, visit and like them on Facebook for reviews and product updates.

Probiotic Action is an advanced acne treatment that uses Probiotics for acne containing the “good bacteria” that is naturally found on healthy human skin. By using probiotics, Probiotic Action is an effective treatment that restores the normal bacteria content on skin, while battling what causes acne. Probiotic Action will successfully clear skin when used as an adult acne treatment while protecting skin against bad bacteria, free radicals, and pollutants*.

*These statements have not been evaluated by the Food and Drug Administration. Probiotic Action is not intended to diagnose, treat, cure or prevent any disease.

For the original version on PRWeb visit:
PRWeb logo

Scratching the Surface of Psoriasis | American Family Medical

Anyone who has struggled with flaky skin or red patches on their elbows, knees and scalp, knows that psoriasis is not just another skin problem, but a chronic condition that can affect your physical and emotional well-being. Psoriasis, a common condition that typically begins between the ages of 15 and 35, is not contagious, but can be uncomfortable, and, at times, embarrassing for those who have been diagnosed. David Oliver, DO, an osteopathic physician from Ocala, Florida explains the common symptoms and provides treatment options for managing psoriasis.

What are the common symptoms? 

According to Dr. Oliver, psoriasis is a skin condition that occurs when the immune system mistakenly speeds up the growth cycle of skin cells. This dysfunction causes a buildup of itchy, thick, red skin with flaky, silver-white patches called scales. Other common symptoms of this condition include:

  1. Severe dandruff on the scalp
  2. Joint pain or aching
  3. Nail changes, including thick yellow-brown nails, dents, and nail lifts off from the skin
  1. Genital lesions in males

How can I ensure a proper diagnosis?

“If you suspect that you might have this condition, schedule a visit with your dermatologist or rheumatologist,” Dr. Oliver advises. Your doctor will review your medical history and perform a physical examination of your skin, scalp, and nails. In rare cases, a diagnosis may require a biopsy. When you meet with your health care provider, Dr. Oliver recommends having an honest dialogue. “Your physician should understand the impact of psoriasis, not only on your physical health, but your emotional health as well,” He says. “Discuss the frequency of flare ups or other medical conditions (such as fever or joint pain), disclose all your current medications, and share information about any family members with psoriasis. The only way to receive the proper diagnosis and treatment is to be open with your primary care provider.”

Is the condition controllable?

Psoriasis flare-ups may go away for a long time, but they return sooner or later. Even though psoriasis is a lifelong condition, it can be controlled with treatment. There are several environmental factors that may trigger an attack of psoriasis or make the condition more difficult to treat,” Dr. Oliver explains. Common triggers include:

  1. Bacterial or viral infections, including strep throat and upper respiratory infections
  2. Dry air or too much/too little sunlight
  3. Injury to the skin, including cuts, burns, and insect bites
  4. Some medicines, including anti-malaria drugs, beta-blockers, and lithium
  5. Too much alcohol

“Treatment is planned according to the type and severity of your condition. The goal of treatment is to control your symptoms and prevent infection,” He adds. Your doctor might prescribe one or a combination of the following treatments:

  1. Topical treatments, such as retinoid containing vitamin D or A, skin lotions with salicylic or lactic acid to remove the scaling, ointments that contain coal tar or anthralin, cortisone creams, or dandruff shampoos.
  2. Systemic treatments (i.e. pills or injections) that affect the body’s immune response.
  3. Phototherapy, a treatment in which your skin is carefully exposed to ultraviolet light.

Prescription for Managing Psoriasis

There is no known way to prevent psoriasis. “Oatmeal baths, keeping the skin clean and moist and avoiding your specific psoriasis triggers, like stress, may help reduce the number of flare-ups,” says Dr. Oliver. “While there may not be a cure for psoriasis, with appropriate treatment, it usually does not affect your general physical health. Work with your doctor to develop a psoriasis treatment plan that’s right for you.”

Preventive medicine is just one aspect of care osteopathic physicians provide. DOs are fully licensed to prescribe medicine and practice in all specialty areas, including surgery. DOs are trained to consider the health of the whole person and use their hands to help diagnose and treat their patients.

What Patients Say Works for Psoriasis | The 23andMe Blog

psoriasis graphicFor the live-updated, fully-labelled, interactive version of this infographic, click here.

By Alexandra Carmichael, Co-Founder of CureTogether

People living with Psoriasis have reported that some of the most effective treatments for their skin include simple interventions like sunlight, salt water, and avoiding stresses.
This is according to a new study by CureTogether, a free resource owned by 23andMe that allows people to share information about their health and treatments.

Psoriasis is one of the most prevalent autoimmune disorders in the United States, affecting an estimated seven million Americans and 125 million worldwide. The condition is characterized by patches of itchy, scaly skin. In its mild form, psoriasis may be just a nuisance, but severe cases can be both painful,  disfiguring and debilitating.

Finding the right treatment can be difficult, so CureTogether asked people living with Psoriasis to rate the effectiveness of 34 different patient-reported treatments.

Participants in the study said they found that phototherapy, cortisone injections, swimming in the ocean, and sunlight were among the most effective, in addition to avoiding stress and triggers and the medications Dovonex and T-Gel. Conversely some common treatments such as oatmeal baths, Epsom salts, and Vitamin D, were among the least effective, according to the study.

Most Effective Rated Treatments for Psoriasis
1. UVB Phototherapy
2. Cortisone injection
3. Salt water/ocean
4. Sunlight
5. Topical corticosteroids
6. Avoid triggers
7. Avoid stress
8. Dovonex
9. UVA Phototherapy
10. T-Gel

Where did this data come from? This is the result of a four-year CureTogether study on Psoriasis, in which 275 people living with the condition shared information about their symptoms and what treatments worked best for them. We’d like to thank those who participated. And just as they shared their experience with treatments, we’re freely and openly sharing the results of the Psoriasis study.

This is part of a regular series of CureTogether research findings. CureTogether’s research findings are different than those made by 23andMe, which look at genetic associations with illness, traits and drug response. But as we continue our work with the CureTogether community, 23andMe hopes to incorporate more of this kind of self-reported information into our own research. CureTogether present its findings just as they are — patient-reported data — to stimulate discussion and generate new insights for further research.

Please tweet, blog, or pass this along to anyone who can benefit or is interested in Psoriasis. Thank you!

You may also want to check out:

Cellceutix Clinical Study on its Anti-Psoriasis Drug Prurisol™ to …

August 12, 2013  |   Press Releases  


Company beginning process to move to national securities exchange

Beverly, MA— August 12, 2013 – Cellceutix Corporation (OTCBB: CTIX) (the “Company”), a clinical stage biopharmaceutical company focused on discovering small molecule drugs to treat unmet medical conditions, including drug-resistant cancers and autoimmune diseases, announces today that the Company is on track to commence a clinical study for its anti-psoriasis drug Prurisol™.  The Company has completed and submitted  all regulatory documents necessary for the clinical study and anticipates receiving the regulatory documents this week allowing for the importation of Prurisol™ into Europe to begin the clinical study.

“We are pleased to inform shareholders that we have now completed the regulatory matters necessary for a clinical study of Prurisol and  that we have been notified by our contract manufacturer, Dr. Reddy’s Laboratories (RDY),  that Prurisol is ready for shipping to the clinical site,” Leo Ehrlich, CEO at Cellceutix stated.  “We are planning to have the drug shipped in August and the trial to commence shortly thereafter. The clinical site has been notified to begin patient recruitment. We are optimistic about the potential for Prurisol™ to reproduce the laboratory results which showed the drug to effectively eliminate all signs of psoriasis.”

In other news, Cellceutix’s clinical trial of its anti-cancer drug Kevetrin is progressing and is presently in the dose escalation phase as maximum tolerated dose (MTD) has not yet been reached.  The testing for p21, a biomarker study at the Harvard Cancer Center lab has not yet begun.  Dr. Krishna Menon, Cellceutix’s Chief Scientific Officer commented, “We understand that there were internal priorities at the lab and because these are very sophisticated and complex tests, the process can be detailed and somewhat time consuming.  We are hopeful that these important biomarker studies will soon be processed and when they are, we will share those results.”

The Company is also pleased to report that it is currently planning to uplist (moving from an over-the-counter stock to a national securities exchange like NASDAQ-CM or NYSE-MKT).  “Due to the Company’s strong financial backing from our $10 million equity line from Aspire Capital, and further progress in our clinical trials, we are intending to move to a senior exchange,” commented Leo Ehrlich, CEO.  “Over the coming weeks we will be interviewing for the positions of independent directors to meet the requirements for an uplisting which we hope will increase liquidity and unlock inherent value in our stock. We will be presenting at the Rodman and Renshaw Annual Global Investment Conference in September where  we will discuss in detail the Company’s progress, growth objectives and plans for 2013- 2014.”


About Kevetrin™

As a completely new class of chemistry in medicine, Kevetrin™ has significant potential to be a major breakthrough in the treatment of solid tumors. Mechanism of action studies showed Kevetrin’s unique ability to affect both wild and mutant types of p53 (often referred to as the “Guardian Angel Gene” or the “Guardian Angel of the Human Genome”) and that Kevetrin strongly induced apoptosis (cell death), characterized by activation of Caspase 3 and cleavage of PARP. Activation of p53 also induced apoptosis by inducing the expression of p53 target gene PUMA. p53 is an important tumor suppressor that acts to restrict proliferation by inducing cell cycle checkpoints, apoptosis, or cellular senescence.

In more than 50 percent of all human carcinomas, p53 is limited in its anti-tumor activities by mutations in the protein itself. Currently, there are greater than 10 million people with tumors that contain inactivated p53, while a similar number have tumors in which the p53 pathway is partially abrogated by inactivation of other signaling components. This has left cancer researchers with the grand challenge of searching for therapies that could restore the protein’s protective function, which Kevetrin appears to be doing the majority of the time.

Further information on the clinical trial, titled “A Phase 1, Open-Label, Dose-Escalation, Safety, Pharmacokinetic and Pharmacodynamic Study of Kevetrin (Thioureidobutyronitrile) Administered Intravenously, in Patients With Advanced Solid Tumors,” is available here.


About Cellceutix

Headquartered in Beverly, Massachusetts, Cellceutix is a publicly traded company under the symbol “CTIX”. It is an emerging bio-pharmaceutical company focused on the development of its pipeline of compounds targeting areas of unmet medical need. Our flagship compound, Kevetrin™, is an anti-cancer drug which has demonstrated the ability in pre-clinical studies to regulate the p53 pathway and attack cancers which have proven resistant to today’s cancer therapies (drug-resistant cancers). Cellceutix also owns the rights to seven other drug compounds, including KM-133, which is in development for psoriasis, and KM-391 for the treatment of the core symptoms of autism. More information is available on the Cellceutix web site at


Safe Harbor Forward-Looking Statements

To the extent that statements in this press release are not strictly historical, including statements as to revenue projections, business strategy, outlook, objectives, future milestones, plans, intentions, goals, future financial conditions, future collaboration agreements, the success of the Company’s development, events conditioned on stockholder or other approval, or otherwise as to future events, such statements are forward-looking, and are made pursuant to the safe harbor provisions of the Private Securities Litigation Reform Act of 1995. The forward-looking statements contained in this release are subject to certain risks and uncertainties that could cause actual results to differ materially from the statements made. Factors that may impact Cellceutix’s success are more fully disclosed in Cellceutix’s most recent public filings with the U.S. Securities and Exchange Commission.



Health: New Research On Psoriasis Treatment « CBS Philly

By Stephanie Stahl

PHILADELPHIA (CBS) – A common skin condition is linked to several potentially life threatening diseases. Will treating the skin condition Psoriasis lower the risk for heart disease? That’s what researchers at Perelman are trying to determine.

Mark Bond has severe psoriasis. The disease causes skin cells to grow rapidly, forming scales and red, itchy patches that can be painful. “It’s embarrassing, people see it and they don’t know what it is, contagious, which it isn’t, but people don’t know that,” said Bond.

Researchers at the Perelman School of Medicine at the University of Pennsylvania looked at more than 9,000 psoriasis patients.  They found as the severity of the skin disease increased, so did the patients chances of pulmonary disease, diabetes, liver disease, heart attack and vascular disease.

Dr. Joel Gelfand the Study Author at the Perelman School of Medicine, University of Pennsylvania says, “If patients have severe disease that doesn’t bother them they are often untreated, and we don’t know if that is potentially dangerous.”

Psoriasis is a common skin condition, affecting as many as seven and a half million Americans. “We are concerned that the link between Psoriasis and cardiovascular disease may be that inflammation is common to both conditions,” Dr. Gelfand said.

In the new study starting at Penn researchers will analyze how treating psoriasis might affect inflammation throughout the body. ”I hope I can help somebody else down the road,” Bond said.

There is no cure for Psoriasis but a variety of different therapy’s can treat symptoms. Perelman is still enrolling Psoriasis volunteers for the new phase of the study.

For more information, visit the links below: